膜
共聚物
甲基丙烯酸酯
高分子化学
单体
聚合物
磷脂
化学工程
化学
渗透
材料科学
有机化学
生物化学
工程类
作者
Kazuhíko Ishihara,Toshihisa Ueda,Nobuo Nakabayashi
出处
期刊:Polymer Journal
[Springer Nature]
日期:1990-05-01
卷期号:22 (5): 355-360
被引量:1006
标识
DOI:10.1295/polymj.22.355
摘要
A methacrylate monomer having the phospholipid polar group, 2-methacryloyloxyethyl phosphorylcholine (MPC) was prepared by an improved method with good yield. MPC was copolymerized with n-butyl methacrylate (BMA). The polymer membranes were prepared from the poly(MPC-co-BMA) by a solution casting method. The membrane adsorbed water well and became a hydrogel structure even MPC mole fraction in the copolymer was 0.04. The water content of the hydrogel membrane increased with increase of MPC units and rise of temperature. These properties of the hydrogel membrane were attributed to the highly hydrophilic phospholipid polar group in the copolymer. Water soluble organic compounds and proteins whose molecular weights were below 104 permeated through the hydrogel membrane. However, the protein could not permeate when the molecular weight was higher than 105.
科研通智能强力驱动
Strongly Powered by AbleSci AI