脂肪组织
成纤维细胞生长因子
受体
白色脂肪组织
FGF21型
医学
内分泌学
内科学
生物
作者
Ai-Luen Wu,Ganesh Kolumam,Scott Stawicki,Yongmei Chen,Jun Li,Jose Zavala‐Solorio,Khanhky Phamluong,Bo Feng,Li Li,Scot Marsters,Lance Kates,Nicholas van Bruggen,Maya Leabman,Anne Wong,David West,Howard M. Stern,Elizabeth Luis,Hok Seon Kim,Daniel G. Yansura,Andrew S. Peterson,Ellen Filvaroff,Yan Wu,Junichiro Sonoda
出处
期刊:Science Translational Medicine
[American Association for the Advancement of Science (AAAS)]
日期:2011-12-14
卷期号:3 (113)
被引量:165
标识
DOI:10.1126/scitranslmed.3002669
摘要
Antibody-mediated activation of fibroblast growth factor receptor 1 reverses the diabetic phenotype in mice, likely by affecting brown adipose tissues.
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