The Bone Mineral Density in Childhood Study: Bone Mineral Content and Density According to Age, Sex, and Race
股骨颈
骨质疏松症
峰值骨量
骨重建
人口
骨矿物质含量
骨龄
骨生长
作者
Heidi J. Kalkwarf,Babette S. Zemel,Vicente Gilsanz,Joan M. Lappe,Mary Horlick,Sharon E. Oberfield,Soroosh Mahboubi,Bo Fan,Margaret M. Frederick,Karen K. Winer,John A. Shepherd
Context: Low bone mass may increase risk of fracture. Several chronic medical conditions, medications, and lifestyle factors affect bone mineral accrual. Appropriate reference values are essential for identification of children with bone deficits. Objective: Our objective was to establish reference curves for bone mineral content (BMC) and density (BMD) in children. Design and Setting: The Bone Mineral Density in Childhood Study is an ongoing longitudinal study in which measurements are obtained annually at five clinical centers in the United States. Participants: Participants included 1554 healthy children (761 male, 793 female), ages 6–16 yr, of all ethnicities. Main Outcome Measures: Scans of the whole body, lumbar spine, hip, and forearm were obtained using dual-energy x-ray absorptiometry. Percentile curves based on three annual measurements were generated using the LMS statistical procedure. Results: BMC of the whole body and lumbar spine and BMD of the whole body, lumbar spine, total hip, femoral n...