亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Relationship Between Final Visual Acuity and Optical Coherence Tomography Findings in Patients with Diabetic Macular Edema Undergoing Anti-VEGF Therapy

光学相干层析成像 糖尿病性黄斑水肿 医学 眼科 视力 血管内皮生长因子受体 黄斑水肿 水肿 糖尿病性视网膜病变 糖尿病 外科 内科学 内分泌学
作者
Seher Eraslan,Özlem Yıldırım,Özer Dursun,Erdem Dinç,Gülhan Örekici Temel
出处
期刊:Türk Oftalmoloji Dergisi [Galenos Yayinevi]
卷期号:50 (3): 163-168 被引量:12
标识
DOI:10.4274/tjo.galenos.2019.91962
摘要

Objectives: To identify the prevalence of findings in optical coherence tomography (OCT) sections before intravitreal anti-VEGF treatment in patients with diabetic macular edema (DME), and to evaluate the relationship between these findings and final visual acuity and number of injections.Materials and Methods: This retrospective study included 296 eyes of 191 patients (104 male, 87 female) who started intravitreal ranibizumab treatment after being diagnosed with DME in the retina unit between January 2013 and April 2017 were included the study.Spectral domain OCT findings at the time of presentation such as presence of serous macular detachment (SD), vitreomacular traction (VMT), and epiretinal membrane (ERM) were recorded.In addition, the regularity of the ellipsoid zone (EZ) and inner retinal layers was also studied. Results:The mean central retinal thickness measured in SD-OCT was 449±81 μm before treatment and 350±96 μm after treatment (p<0.001).SD was detected in 155 eyes (52.4%),ERM in 67 eyes (22.6%), and VMT in 9 eyes (3%).Thirty eyes (10.1%) had disorganization of the retinal inner layers (DRIL) and 54 eyes (18.2%) had EZ deterioration.The presence of ERM, EZ irregularity, and DRIL were associated with significantly lower final visual acuity (p<0.0001), while there was no relationship between pre-treatment SD and final visual acuity (p=0.11).Injection number was higher in eyes with SD and ERM compared to those without, but this difference was statistically significant only in the presence of SD (p=0.01 and p=0.59, respectively).There was no difference in injection number according to EZ irregularity or presence of DRIL. Conclusion:The coexistence of SD with DME was associated with increased need for treatment but not with final visual acuity.EZ irregularities, DRIL, and ERM are findings that negatively affect visual acuity.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
NexusExplorer应助Luo采纳,获得10
1秒前
12秒前
Luo发布了新的文献求助10
18秒前
wintersss完成签到,获得积分10
21秒前
29秒前
Plum22发布了新的文献求助20
33秒前
廖庭毅发布了新的文献求助10
37秒前
40秒前
1分钟前
山是山三十三完成签到 ,获得积分10
1分钟前
核桃发布了新的文献求助10
1分钟前
斯文败类应助科研通管家采纳,获得10
1分钟前
NexusExplorer应助科研通管家采纳,获得10
1分钟前
杨怂怂完成签到 ,获得积分10
2分钟前
2分钟前
2分钟前
朱朱子完成签到 ,获得积分10
3分钟前
Akim应助科研通管家采纳,获得10
4分钟前
GingerF应助科研通管家采纳,获得100
4分钟前
传奇3应助科研通管家采纳,获得10
4分钟前
4分钟前
4分钟前
4分钟前
Plum22发布了新的文献求助20
4分钟前
HAG完成签到,获得积分20
4分钟前
Perry完成签到,获得积分10
5分钟前
江枫渔火完成签到 ,获得积分10
5分钟前
MchemG应助科研通管家采纳,获得10
6分钟前
闫雪完成签到,获得积分10
6分钟前
6分钟前
闫雪发布了新的文献求助10
6分钟前
Plum22发布了新的文献求助20
6分钟前
直觉应助闫雪采纳,获得10
6分钟前
蚂蚁踢大象完成签到 ,获得积分10
7分钟前
hgsgeospan完成签到,获得积分10
7分钟前
直率的笑翠完成签到 ,获得积分10
7分钟前
hgs完成签到,获得积分10
7分钟前
7分钟前
MchemG应助科研通管家采纳,获得10
7分钟前
JamesPei应助科研通管家采纳,获得10
7分钟前
高分求助中
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3990105
求助须知:如何正确求助?哪些是违规求助? 3532119
关于积分的说明 11256456
捐赠科研通 3271016
什么是DOI,文献DOI怎么找? 1805171
邀请新用户注册赠送积分活动 882288
科研通“疑难数据库(出版商)”最低求助积分说明 809228