化学
抗生素
自然(考古学)
组合化学
生物化学
生物
古生物学
作者
Jiangkun Dai,Rui Han,Yu-Jie Xu,Na Li,Junru Wang,Wenjia Dan
标识
DOI:10.1016/j.bioorg.2020.103922
摘要
The discovery of novel antibacterial molecules plays a key role in solving the current antibiotic crisis issue. Natural products have long been an important source of drug discovery. Herein, we reviewed 256 natural products from 11 structural classes in the period of 2016-01/2020, which were selected by SciFinder with new compounds or new structures and MICs lower than 10 μg/mL or 10 μM as criterions. This review will provide some effective antibacterial lead compounds for medicinal chemists, which will promote the antibiotics research based on natural products to the next level.
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