The fence technique: Autogenous bone graft versus 50% deproteinized bovine bone matrix / 50% autogenous bone graft—A clinical double‐blind randomized controlled trial

医学 牙科 骨移植 外科 随机对照试验 显著性差异 双盲 内科学 病理 安慰剂 替代医学
作者
Mauro Merli,Michele Nieri,Giorgia Mariotti,Marco Merli,Lorenzo Franchi,Bernardo Quiroga Souki,Lorenzo Franchi,Bernardo Quiroga Souki
出处
期刊:Clinical Oral Implants Research [Wiley]
卷期号:31 (12): 1223-1231 被引量:10
标识
DOI:10.1111/clr.13670
摘要

Abstract Objectives The aim of this short‐term double‐blind, parallel, randomized clinical trial was to compare bone augmentation grafting with 100% autogenous bone (AB) or 50% deproteinized bovine bone matrix (DBBM)/ 50% autogenous bone (BOAB) using a guided bone regeneration procedure, the fence technique, in a two‐stage implant placement. Material and methods Partially edentulous patients with extensive three‐dimensional osseous defects were included in this study. The main outcome measure was the differences in bone volume from pre‐surgery (T1) to 6 months post‐surgery (T2). Bone height, chair‐time, pain, functional limitation, and complications were also assessed. Results Fifteen patients were allocated to the AB group and 15 patients to the BOAB group. The difference in bone volume from T1 to T2 was 648 mm 3 for the AB group and 869mm 3 for the BOAB group (difference between groups 221 mm 3 , 95% CI from −363 to 804, p = .442). The surgery pain VAS was 1.6 for the AB group and 2.3 for the BOAB group (difference between groups 0.8, 95% CI from 0.0 to 1.5, p = .045 favoring the AB group). The height difference in bone from T1 to T2 was 2.2 mm for the AB group and 3.7 mm for the BOAB group (difference between groups 1.5mm, 95% CI from 0.1 to 2.9, p = .038 favoring the BOAB group). For complications, chair‐time, post‐surgery pain, and functional limitation, there were no differences between AB and BOAB. Conclusions No significant differences, except for surgery pain VAS and difference in bone height, were observed in this trial comparing grafting with AB or BOAB.
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