阿替唑单抗
医学
PD-L1
化疗
单克隆抗体
肿瘤科
肺癌
程序性细胞死亡1
单克隆
内科学
铂金
免疫疗法
彭布罗利珠单抗
抗体
癌症
免疫学
催化作用
化学
生物化学
作者
Roy S. Herbst,Giuseppe Giaccone,Filippo de Marinis,Niels Reinmuth,A. Vergnenégre,Carlos H. Barrios,Masahiro Morise,Enriqueta Felip,Zoran Andrić,Sarayut Lucien Geater,Mustafa Özgüroğlu,Wei Zou,Alan Sandler,Ida Enquist,Kimberly M. Komatsubara,Yu Deng,Hiroshi Kuriki,Xiaohui Wen,Mark L. McCleland,Simonetta Mocci,Jacek Jassem,David R. Spigel
标识
DOI:10.1056/nejmoa1917346
摘要
The efficacy and safety of the anti–programmed death ligand 1 (PD-L1) monoclonal antibody atezolizumab, as compared with those of platinum-based chemotherapy, as first-line treatment for patients with metastatic non–small-cell lung cancer (NSCLC) with PD-L1 expression are not known.
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