Effect of hemoperfusion on serum cytokines of children with Henoch-Schonlein purpura

Objective To investigate the effect of hemoperfusion on serum cytokines of children with Henoch-Schonlein purpura(HSP).Methods Nine children with HSP were treated with hemoperfusion for 3 times,and serum TNF-α,IL-6,IL-8 changes before and after hemoperfusion were detected.Results Hemoperfusion could efficiently clean serum TNF-α ( P ＜ 0.05 ) and had partial effect on the level of IL-6,but had no influence on IL-8.Hemoperfusion had obvious effect on relieving clinical symptoms.Conclusions Hemoperfusion has beneficial effect on Henoch-Schonlein purpura by cleaning serum cytokines. Key words: Hemoperfusion; Henoch-Schonlein purpura; Cytokine; Children