医学
发病机制
肾病
生物标志物
病态的
肾活检
肾小球肾炎
活检
病理
免疫学
肾
内科学
内分泌学
生物
生物化学
糖尿病
出处
期刊:International Journal of Pediatrics
日期:2017-09-26
卷期号:44 (9): 619-622
标识
DOI:10.3760/cma.j.issn.1673-4408.2017.09.009
摘要
IgA nephropathy(IgAN)is the most common form of primary glomerulonephritis, and caused by multi-genes and multi-factors.However, pathological mechanisms are not fully understood.Although renal biopsy is the gold standard for diagnosing IgAN, it is very difficult to carry out in children because it is an invasive test, and due to the limit of the puncture site and glomeruli amount, renal biopsy could not accurately reflect the severity of glome-rulopathy.Therefore, many researchers are trying to find the ideal non-invasive biomarker for IgAN.The research progress of pathogenesis and noninvasive biomarkers of IgAN will be introduced in this paper.
Key words:
IgA nephropathy; Pathogenesis; Non-invasive biomarker
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