血脑屏障
疾病
风险因素
认知功能衰退
阿尔茨海默病
医学
神经科学
内科学
痴呆
心理学
中枢神经系统
作者
Makoto Ishii,Costantino Iadecola
出处
期刊:Nature
[Springer Nature]
日期:2020-04-29
卷期号:581 (7806): 31-32
被引量:54
标识
DOI:10.1038/d41586-020-01152-8
摘要
People who carry the gene variant APOE4 are at higher-than-average risk of developing Alzheimer’s disease. It emerges that this variant is linked to defects in the blood–brain barrier and subsequent cognitive decline. A link between APOE4 and breakdown of the blood–brain barrier.
科研通智能强力驱动
Strongly Powered by AbleSci AI