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An institutional review of 10 cases of spinal hemangiopericytoma/solitary fibrous tumor

医学 血管外皮细胞瘤 孤立性纤维性肿瘤 放射性武器 腰椎 放射治疗 外科 组织病理学 回顾性队列研究 放射科 川地34 病理 干细胞 遗传学 生物
作者
Raghav Singla,Pankaj Kumar Singh,Gaurav Khanna,Vaishali Suri,Deepak Agarwal,P. Sarat Chandra,Shashank S. Kale,AK Mahapatra
出处
期刊:Neurology India [Medknow Publications]
卷期号:68 (2): 448-448 被引量:6
标识
DOI:10.4103/0028-3886.284374
摘要

Background: Spinal hemangiopericytoma is very rare tumors with only a few case reports and one case series. We have treated ten patients between 2004 and 2017 and, thus, present a retrospective review of our patients with a focus on clinical presentation, radiological features, management, pathology, and outcome.Materials and Methods: Histopathological data were reviewed in all the cases and clinical and follow-up details were collected from data available in our department.Results: There were five males and five females, including one pediatric patient. The mean age of the patients was 34.7 years (Range 12–52 years). Dorsal, cervical, and lumbar spine involvement were found in five, four, and one patient, respectively. Intradural extramedullary tumor was the most common tumor and all patients presented motor weaknesses. Gross total resection of the tumor was done in seven patients and six patients received postoperative radiotherapy. Histopathology showed anaplastic tumor in two cases with high MIB-1 labelling index. Most patients were positive for CD34, vimentin, mic-2, and bcl-2. While the seven patients who underwent gross total resection improved significantly and were self-ambulatory in the follow-up period, two patients who underwent subtotal resection expired due to tumor metastasis.Conclusion: Spinal hemangiopericytoma is a very rare tumor. We present a series of cases treated at our institute for the same. Gross total resection is the goal and radiotherapy should be given in case of residual tumor or high-grade tumors. Prognosis is good after gross total excision and functional recovery can be expected in most patients.
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