Investigation on incidence of childhood type 1 diabetes mellitus in Shenzhen

Objective:To get the data of childhood type 1 diabetes mellitus (T1DM) incidence in Shenzhen,provide a basis for further study of T1DM.Methods:A retrospective epidemiological study on the incidence of T1DM among children aged 0～14 years was conducted in Shenzhen from January 1999 to December 2006 by capture recapture method (CRM).Results:39 children aged 0～14 years with T1DM were found from 1999 to 2006,including 19 boys and 20 girls;the mean incidence was 0.737 0/100 000 per year; projected incidence was 0.755 9/100 000 per year (95%CI:0.718 1~0.793 7/100 000);the incidence of 2004 was the highest (1.965 4/100 000 per year),while the incidence of children aged 10~14 years was the highest (1.270 0/100 000 per year);there was no significant difference in the T1DM incidence between boys (0.714 5/100 000 per year) and girls (0.759 8/100 000 per year) (χ2=0.04,P0.05 ).Conclusion:The incidence of T1DM is 0.737 0/100 000 per year,projected incidence is 0.755 9/100 000 per year,the incidence of children aged 10~14 years is the highest,there is no significant difference in the T1DM incidence between boys and girls,compared to other countries,the incidence of T1DM in Shenzhen is low,but compared to other cities in China,the incidence is a little high.