Use of Vivostat® Autologous Fibrin Sealant in Thyroid Surgery

医学 血清瘤 密封剂 外科 并发症 纤维蛋白 脊髓切除术 甲状腺癌 纤维蛋白组织粘合剂 纤维蛋白胶 甲状腺切除术 甲状腺 止血 内科学 喉切除术
作者
Antonella Pino,Francesco Frattini,Hui Sun,Daqi Zhang,Che-Wei Wu,Hoon Yub Kim,Gianlorenzo Dionigi
出处
期刊:Surgical technology international [Surgical Technology Online]
被引量:2
标识
DOI:10.52198/21.sti.38.so1441
摘要

Introduction: Post-thyroidectomy hemorrhage is a rare but potentially life-threatening and unpredictable complication of thyroid surgery. Therefore, intraoperative bleeding control and hemostasis are crucial. However, the most efficient, cost-effective, and standardized way to achieve this is not clear. This study aimed to evaluate the outcome of total thyroidectomy (TT) and partial thyroidectomy (PT) performed using the Vivostat® hemostatic system (Vivostat A/S, Lillerød, Denmark). Methods: Patients underwent TT and PT for benign and malignant diseases (multinodular goiter, Graves’ disease, differentiated thyroid carcinoma). The primary endpoint was 1st-day postoperative drain output and bleeding that required reintervention. Secondary endpoints included surgery duration and postsurgical complications (vocal fold palsy, hypocalcemia, seroma, wound infection). Results: Between October 2020 and December 2020, 56 patients were enrolled; 69.6% female; mean age 49.5 years. The mean 24-h drain output was 40 ml. No redo surgery was needed. Seroma was present in 5.3% of cases; no permanent vocal palsy or hypocalcemia was observed. Conclusion: This study shows that the Vivostat® system is both safe and effective for hemostasis during thyroid surgery.

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