Association of Pediatric ASPECTS and NIH Stroke Scale, Hemorrhagic Transformation, and 12-Month Outcome in Children With Acute Ischemic Stroke.

医学 冲程(发动机) 小儿中风 改良兰金量表 缺血性中风 脑出血
作者
Lauren A. Beslow,Arastoo Vossough,Rebecca Ichord,Nedelina Slavova,Maggie L.Y. Yau,Jay Gajera,Belinda Stojanovski,Malik M. Adil,Jake Breimann,Alexandra Kimmel,Mark T Mackay
出处
期刊:Neurology [Lippincott Williams & Wilkins]
卷期号:97 (12) 被引量:1
标识
DOI:10.1212/wnl.0000000000012558
摘要

Background and Objectives We aimed to determine whether a modified pediatric Alberta Stroke Program Early CT Score (modASPECTS) is associated with clinical stroke severity, hemorrhagic transformation, and 12-month functional outcomes in children with acute arterial ischemic stroke (AIS). Methods Children (age 29 days– Results One hundred thirty-one children were included; 91 were ≥2 years of age. Median time from stroke to MRI was 1 day (interquartile range [IQR] 0–1 day). Median modASPECTS was 4 (IQR 3–7). ModASPECTS correlated with PedNIHSS score (ρ = 0.40, p = 0.0001). ModASPECTS was associated with hemorrhagic transformation (odds ratio [OR] 1.13, 95% confidence interval [CI] 1.02–1.25, p = 0.018). Among children with follow-up (n = 128, median 12.2 months, IQR 9.5–15.4 months), worse outcomes were associated with higher modASPECTS (common OR 1.14, 95% CI 1.04–1.24, p = 0.005). The association between modASPECTS and outcome persisted when we adjusted for age at stroke ictus and the presence of tumor or meningitis as stroke risk factors (common OR 1.14, 95% CI 1.03–1.25, p = 0.008). Discussion ModASPECTS correlates with PedNIHSS scores, hemorrhagic transformation, and 12-month functional outcome in children with acute AIS. Future pediatric studies should evaluate its usefulness in predicting symptomatic intracranial hemorrhage and outcome after acute revascularization therapies. Classification of Evidence This study provides Class II evidence that the modASPECTS on MRI is associated with stroke severity (as measured by the baseline PedNIHSS score), hemorrhagic transformation, and 12-month outcome in children with acute supratentorial ischemic stroke.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
李治稳发布了新的文献求助10
刚刚
2秒前
liu发布了新的文献求助10
3秒前
5秒前
严晓博完成签到,获得积分10
6秒前
6秒前
zhoup发布了新的文献求助20
7秒前
zzl-2000完成签到,获得积分10
7秒前
boshi发布了新的文献求助10
7秒前
xiaowei发布了新的文献求助10
8秒前
严晓博发布了新的文献求助10
8秒前
jing发布了新的文献求助30
9秒前
9秒前
Jzhu96发布了新的文献求助10
10秒前
10秒前
CC完成签到,获得积分10
11秒前
田様应助老迟到的沛萍采纳,获得10
11秒前
斯文静竹完成签到,获得积分10
11秒前
花海完成签到,获得积分10
12秒前
12秒前
wddddd发布了新的文献求助10
14秒前
ChatGPT发布了新的文献求助10
15秒前
开心尔芙发布了新的文献求助30
16秒前
FashionBoy应助zhangheng采纳,获得10
16秒前
liu完成签到,获得积分10
16秒前
17秒前
17秒前
强砸完成签到,获得积分10
18秒前
xu关闭了xu文献求助
18秒前
所所应助dyy采纳,获得10
19秒前
内向寒云发布了新的文献求助10
20秒前
华仔应助九卫采纳,获得10
21秒前
宇_y246发布了新的文献求助10
21秒前
22秒前
幸福拖拉机完成签到,获得积分10
22秒前
CipherSage应助方仔采纳,获得10
23秒前
情怀应助pipi采纳,获得10
23秒前
Ion发布了新的文献求助10
24秒前
25秒前
lisa完成签到,获得积分10
26秒前
高分求助中
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
Effective Learning and Mental Wellbeing 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975339
求助须知:如何正确求助?哪些是违规求助? 3519670
关于积分的说明 11199199
捐赠科研通 3256002
什么是DOI,文献DOI怎么找? 1798043
邀请新用户注册赠送积分活动 877386
科研通“疑难数据库(出版商)”最低求助积分说明 806305