电合成
电化学
化学
分子
有机分子
组合化学
封面(代数)
激进的
小分子
有机化学
电极
工程类
物理化学
生物化学
机械工程
作者
Camila M. Kisukuri,Vitor A. Fernandes,José A. C. Delgado,Andreas P. Häring,Márcio W. Paixão,Siegfried R. Waldvogel
标识
DOI:10.1002/tcr.202180905
摘要
The cover picture displays fluoroalkyl radicals as reactive intermediates in the electrochemical (per)fluoroalkylation and representative examples of electrochemically fluoroalkylated small molecules. The installation of fluoroalkyl moieties into drug candidates significantly promotes their potency. Electrosynthesis is a sustainable and powerful technology to tackle this challenging synthetic task. Consequently, electrochemical fluoroalkylation of small organic molecules has become a vivid area of research, which is surveyed by S. R. Waldvogel and co-workers in their Record Review (DOI: 10.1002/tcr.202100065).
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