异丙苯
过氧化氢异丙苯
化学
催化作用
激进的
丙酮
选择性
溶剂
光化学
有机化学
作者
Qiuting Lu,Gaoquan Shi,Hongyu Zhou,Enxian Yuan,Chong Chen,Lijun Ji
标识
DOI:10.1016/j.apcata.2021.118441
摘要
Cumyl hydroperoxide (CHP) is an important intermediate for the production of phenol/acetone, but suffers from severe reaction conditions and a low yield industrially. Here, an efficient transformation from cumene to CHP was developed. Different solvents were modulated for cumene oxidation catalyzed by NHPI/Co, and reaction network and mechanisms were investigated methodically. Hexafluoroisopropanol (HFIP) markedly promoted the transformation from cumene to CHP compared to other solvents at room temperature. A cumene conversion high up to 64.3% were observed with a selectivity to CHP of 71.7%. The solvent HFIP exhibited a significant promotion on cumene oxidation due to its contribution to the enhancement of the concentration of PINO radicals. Moreover, cumyl, cumyl oxyl and methyl radicals were captured by TEMPO and analyzed by HRMS, and the reaction paths and mechanisms from cumene to products were inferred. The preparation method discovered in this work may open an access to the production of CHP.
科研通智能强力驱动
Strongly Powered by AbleSci AI