Python(编程语言)
注释
标杆管理
计算机科学
软件
基因组学
基因组
基因注释
计算生物学
生物
拷贝数变化
参考基因组
编码
管道(软件)
遗传学
源代码
情报检索
基因
人工智能
营销
业务
程序设计语言
操作系统
作者
Felipe A. Simão,Robert M. Waterhouse,Panagiotis Ioannidis,Evgenia V. Kriventseva,Evgeny M. Zdobnov
出处
期刊:Bioinformatics
[Oxford University Press]
日期:2015-06-09
卷期号:31 (19): 3210-3212
被引量:8406
标识
DOI:10.1093/bioinformatics/btv351
摘要
Abstract Motivation: Genomics has revolutionized biological research, but quality assessment of the resulting assembled sequences is complicated and remains mostly limited to technical measures like N50. Results: We propose a measure for quantitative assessment of genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. We implemented the assessment procedure in open-source software, with sets of Benchmarking Universal Single-Copy Orthologs, named BUSCO. Availability and implementation: Software implemented in Python and datasets available for download from http://busco.ezlab.org. Contact: evgeny.zdobnov@unige.ch Supplementary information: Supplementary data are available at Bioinformatics online.
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