Chiral β- and γ-aminoalcohols derived from (+)-camphor and (−)-fenchone as catalysts for the enantioselective addition of diethylzinc to benzaldehyde

Abstract The addition of Me 3 SiCN and LiCH 2 CN to (+)-camphor and (−)-fenchone, respectively, followed by reduction leads to chiral β- and γ-aminoalcohols. The enantioselectivities realized using these aminoalcohols as ligands in the addition of Et 2 Zn to benzaldehyde were lower than those obtained using the corresponding δ-aminoalcohols.