效应器
生物
归巢(生物学)
抗原
细胞生物学
神经科学
功能(生物学)
免疫学
存储单元
生态学
量子力学
物理
电压
晶体管
作者
Federica Sallusto,Jens Geginat,Antonio Lanzavecchia
出处
期刊:Annual Review of Immunology
[Annual Reviews]
日期:2004-04-01
卷期号:22 (1): 745-763
被引量:2805
标识
DOI:10.1146/annurev.immunol.22.012703.104702
摘要
The memory T cell pool functions as a dynamic repository of antigen-experienced T lymphocytes that accumulate over the lifetime of the individual. Recent studies indicate that memory T lymphocytes contain distinct populations of central memory (TCM) and effector memory (TEM) cells characterized by distinct homing capacity and effector function. This review addresses the heterogeneity of TCM and TEM, their differentiation stages, and the current models for their generation and maintenance in humans and mice.
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