量子点
淋巴系统
荧光
癌症转移
淋巴
材料科学
波长
生物医学工程
光电子学
光学
纳米技术
癌症
病理
转移
物理
医学
内科学
作者
Hisataka Kobayashi,Yukihiro Hama,Yoshinori Koyama,Tristan Barrett,Celeste A.S. Regino,Yasuteru Urano,Peter L. Choyke
出处
期刊:Nano Letters
[American Chemical Society]
日期:2007-05-26
卷期号:7 (6): 1711-1716
被引量:304
摘要
Quantum dots can be used to perform multicolor images with high fluorescent intensity and are of a nanosize suitable for lymphatic imaging via direct interstitial injection. Here simultaneous multicolor in vivo wavelength-resolved spectral fluorescence lymphangiography is shown using five quantum dots with similar physical sizes but different emission spectra. This allows noninvasive and simultaneous visualization of five separate lymphatic flows draining and may have implications for predicting the route of cancer metastasis into the lymph nodes.
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