A Biomechanical Study of Regional Endplate Strength and Cage Morphology as It Relates to Structural Interbody Support

医学 笼子 形态学(生物学) 解剖 物理医学与康复 口腔正畸科 结构工程 动物 生物 工程类
作者
Thomas G. Lowe,Shukor Hashim,Lucas A. Wilson,Michael O’Brien,David A. Smith,Molly J. Diekmann,Julie M. Trommeter
出处
期刊:Spine [Lippincott Williams & Wilkins]
卷期号:29 (21): 2389-2394 被引量:217
标识
DOI:10.1097/01.brs.0000143623.18098.e5
摘要

An in vitro biomechanical investigation to quantify the endplates resistance to compressive loads, in the thoracic and lumbar spine. Comparisons were made to determine the regional strength of the endplate, the optimal size and geometry of interbody support, and the effects of endplate removal on structural strength.To biomechanically assess the regional variation of endplate strength in the thoracic and lumbar spine, the optimal geometry and cross-sectional area for structural interbody support, and endplate preparation techniques with respect to endplate failure or subsidence.Anterior column interbody support plays an important role in spinal reconstruction. Subsidence of interbody structural support is a common problem and may be related to regional weakness of the endplate, the size and/or geometry of structural support, and the preparation of the endplate. Biomechanical data related to these issues should be of importance to spine surgeons and reduce the risk of subsidence and its inherent complications.The indentation tests were performed in three subgroups, each with a different set of test variables. The first test consisted of 65 vertebrae at six different endplate test positions using a 9.53-mm diameter indenter. The second test was performed on 48 vertebrae at a central endplate test site using three hollow and two solid cylindrical indenters of varying diameter. The third test was done using 24 vertebrae with the endplate intact, partially removed, or fully removed. All tests were run using human cadaveric specimen using both the superior and inferior endplates. The maximum load to failure (MLF) was determined for each test performed.For all levels tested, the highest MLF occurred in the posterolateral region of the endplate. The lowest value occurred in the central and anterocentral regions for levels T7-L5 and T1-T6, respectively. Hollow indenters with a small diameter had the lowest MLF, whereas solid large-diameter indenters had the highest MLF. The ultimate compressive strength for all hollow indenters was significantly higher than all solid indenters. There was a significant reduction in the endplate strength with the complete removal of the endplate.The posterolateral region of the endplate provides the greatest resistance to subsidence while the central region provides the least resistance. A larger-diameter solid support has the greater MLF and the lower the risk of subsidence, suggesting a more efficient transfer of force to the endplate with the hollow indenters. Parameters such as the geometry of structural support and the position and preparation of the endplate can influence the resistance of an interbody support to subside. Partial removal of the endplate may provide both, for adequate mechanical advantage and a highly vascular site for fusion.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
桐桐应助幸福的杨小夕采纳,获得10
1秒前
韩麒嘉完成签到 ,获得积分10
3秒前
聪慧的凝海完成签到 ,获得积分0
12秒前
12秒前
wwb发布了新的文献求助10
15秒前
phil完成签到 ,获得积分10
15秒前
23秒前
高高菠萝完成签到 ,获得积分10
23秒前
滴滴滴完成签到 ,获得积分10
23秒前
yangsi完成签到 ,获得积分10
26秒前
量子星尘发布了新的文献求助10
27秒前
30秒前
酷炫葵阴发布了新的文献求助10
35秒前
ORANGE完成签到,获得积分10
37秒前
思源应助松松采纳,获得20
41秒前
共享精神应助酷炫葵阴采纳,获得10
43秒前
丝丢皮得完成签到 ,获得积分10
44秒前
45秒前
xfy完成签到,获得积分10
49秒前
阳炎完成签到,获得积分10
51秒前
行云流水完成签到,获得积分10
52秒前
53秒前
冷酷尔琴发布了新的文献求助10
57秒前
青水完成签到 ,获得积分10
1分钟前
量子星尘发布了新的文献求助10
1分钟前
1分钟前
冷酷尔琴完成签到,获得积分10
1分钟前
onevip完成签到,获得积分0
1分钟前
小莫完成签到 ,获得积分10
1分钟前
1分钟前
theseus完成签到,获得积分10
1分钟前
胡楠完成签到,获得积分10
1分钟前
北国雪未消完成签到 ,获得积分10
1分钟前
李振博完成签到 ,获得积分10
1分钟前
1分钟前
雪妮完成签到 ,获得积分10
1分钟前
松松发布了新的文献求助20
1分钟前
1分钟前
iwsaml完成签到 ,获得积分10
1分钟前
Caden完成签到 ,获得积分10
1分钟前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038029
求助须知:如何正确求助?哪些是违规求助? 3575740
关于积分的说明 11373751
捐赠科研通 3305559
什么是DOI,文献DOI怎么找? 1819224
邀请新用户注册赠送积分活动 892652
科研通“疑难数据库(出版商)”最低求助积分说明 815022