Carcinoma pancreas and fibrocalcific pancreatic diabetes: a dual association for weight loss.

A 52-year-old man presented with upper abdominal pain and weight loss of 10 kg over 6 months. He had suffered from diabetes mellitus for the past 10 years and was on oral antidiabetic agents. He did not drink alcoholic. He had a history suggestive of steatorrhoea, which worsened following the intake of a fat-rich meal. On clinical examination, his body mass index was 20.5 kg/m2 and there was no evidence of nutritional deficiencies. Abdominal examination was unremarkable. His biochemical evaluation was as follows—haemoglobin 12.7 g/dL (normal range (N) 13–18), glycated haemoglobin 10.5% (N <5.7), S.alkaline phosphatase 90 U/L (N 40–125), serum creatine: 0.9 mg/dL (N 0.6–1.2). An abdomen X-ray showed pancreatic calcification (figure 1 …