Changing everyday memory behaviour in amnestic mild cognitive impairment: A randomised controlled trial

Abstract One of the defining differences between mild cognitive impairment (MCI) and dementia is the degree of independence in everyday activities. Effecting memory-related behavioural change in MCI could help maintain daily function and prolong the time before onset of dependency. However, it is well known that changing previously well-established behaviours is difficult to achieve. We conducted a randomised controlled trial to evaluate the effectiveness of a multidisciplinary group-based intervention programme in changing everyday memory behaviour in individuals with amnestic MCI. The intervention provided evidenced-based memory training and lifestyle education to optimise memory behaviour. Fifty-four participants were randomly assigned to treatment or waitlist-control conditions. Consistent with our primary goal, treatment participants showed an increase in memory-strategy knowledge and use from pre-test to immediate post-test, and these gains were maintained at three-month post-test relative to waitlist controls. There were no group differences in memory beliefs or on laboratory tests of objective memory performance. The increase in memory-strategy knowledge and use was associated with the degree of participation in the programme. Individuals with MCI, therefore, can acquire and maintain knowledge about memory strategies and, importantly, can change their everyday memory behaviour by putting this knowledge into practice. This incorporation of practical memory strategies into daily routines could potentially provide the means for maintaining functional independence by individuals with MCI, an issue to be addressed in future research. The study was supported by a grant from the Alzheimer's Society of Canada and by Dejardins Financial and Richter Usher and Vineberg. Thanks are extended to Guy Proulx, Dmytro Rewilak, Renee Climans, Arlene Consky, Cheli Barokas-Agate, Dierdre vanLane, Corey Mackenzie, and Carol Greenwood for help developing and administering the programme; to Kathryn Stokes for referring participants; and to Brent Hayman-Abello, Linda Moradzadeh, Triti Namiranian, Chris Alappat, Julia Cheng, and Alexandre Proulx for testing, scheduling, and managing data.