加巴喷丁
谵妄
医学
安慰剂
麻醉
随机对照试验
临床试验
外科
内科学
重症监护医学
替代医学
病理
作者
Jacqueline M. Leung,Laura P. Sands,María Antonieta Rico,Karin L. Petersen,Michael C. Rowbotham,Jørgen B. Dahl,Christopher P. Ames,Dean Chou,Philip R. Weinstein
出处
期刊:Neurology
[Ovid Technologies (Wolters Kluwer)]
日期:2006-08-17
卷期号:67 (7): 1251-1253
被引量:164
标识
DOI:10.1212/01.wnl.0000233831.87781.a9
摘要
In this randomized pilot clinical trial, the authors tested the hypothesis that using gabapentin as an add-on agent in the treatment of postoperative pain reduces the occurrence of postoperative delirium. Postoperative delirium occurred in 5/12 patients (42%) who received placebo vs 0/9 patients who received gabapentin, p = 0.045. The reduction in delirium appears to be secondary to the opioid-sparing effect of gabapentin.
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