丁香醛
香兰素
苯甲醛
化学
醛
阿卡波糖
IC50型
立体化学
生物化学
酶
催化作用
体外
作者
Dinh Tri Mai,Tien Le,Tan N. Nguyen,Nhat Minh Phan,Huu Phuc Nguyen,Thi H. O. Nguyen,Le Chung Tran
标识
DOI:10.1080/14786419.2014.1003929
摘要
From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new (1) and six known aldehyde compounds (2–7) were isolated by various chromatography methods. Based on their spectroscopic data, these compounds were identified as (Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl) benzaldehyde (1), p-hydroxybenzaldehyde (2), syringaldehyde (3), (E)-ferulaldehyde (4), (E)-sinapinaldehyde (5), vanillin (6) and 5-hydroxymethylfurfual (7). The α-glucosidase inhibitory activity of all compounds was measured. The isolated compounds (1–6) showed better α-glucosidase inhibitory activity (IC50 values ranging from 36.5 to 192.4 μM) than the standard drug acarbose (IC50 = 214.5 μM).
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