Temporal Trends in Survival to Adulthood Among Patients Born With Congenital Heart Disease From 1970 to 1992 in Belgium

医学 左心发育不良综合征 置信区间 预期寿命 心脏病 儿科 生存分析 年轻人 内科学 人口 环境卫生
作者
Philip Moons,Lore Bovijn,Werner Budts,Ann Belmans,Marc Gewillig
出处
期刊:Circulation [Lippincott Williams & Wilkins]
卷期号:122 (22): 2264-2272 被引量:623
标识
DOI:10.1161/circulationaha.110.946343
摘要

Over the past decades, the life expectancy of individuals with congenital heart disease (CHD) has increased significantly. However, precise estimates for survival to adulthood are scarce for patients with CHD. We investigated the proportion of CHD patients born between 1990 and 1992 who survived into adulthood. We also compared their survival with that of CHD patients born in earlier eras and evaluated survival as a function of the type of heart defect.We reviewed the CHD program administrative and clinical database at the University Hospitals Leuven (Leuven, Belgium) and analyzed the records of 7497 CHD patients born from 1970 to 1992. Survival to 18 years of age in patients born between 1990 and 1992 was 88.6% (95% confidence interval [CI], 86.3% to 90.5%), which was significantly greater than that of patients born in previous decades (P<0.0001). For patients born between 1990 and 1992, survival into adulthood for those with mild heart defects was 98.0% (95% CI, 95.8% to 99.1%), whereas survival for those with moderate- and severe-complexity heart defects was 90.0% (95% CI, 86.8% to 92.5%) and 56.4% (95% CI, 47.4% to 64.5%), respectively. Analysis per heart defect confirmed these findings, demonstrating that patients with univentricular heart (49.1% [95% CI, 30.8% to 65.1%]) and hypoplastic left heart syndrome (7.5% [95% CI, 0.6% to 26.6%]) had the poorest survival rate.This study demonstrates that almost 90% of children with CHD have the prospect of surviving into adulthood.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
xue完成签到 ,获得积分10
1秒前
liars完成签到 ,获得积分10
1秒前
搞怪人雄完成签到,获得积分10
4秒前
落后的夜阑完成签到,获得积分10
4秒前
大橙子发布了新的文献求助10
7秒前
彪行天下完成签到,获得积分10
12秒前
danli完成签到 ,获得积分10
13秒前
guangyu完成签到,获得积分10
15秒前
学术老6完成签到,获得积分10
16秒前
c123完成签到 ,获得积分10
18秒前
恐怖稽器人完成签到,获得积分10
18秒前
WXR完成签到,获得积分10
19秒前
科研小白完成签到,获得积分10
19秒前
20秒前
可爱丸子完成签到,获得积分10
20秒前
皮汤汤完成签到 ,获得积分10
21秒前
JXDYYZK完成签到,获得积分10
22秒前
SYLH应助lu采纳,获得10
22秒前
Servant2023完成签到,获得积分10
22秒前
鸽子的迷信完成签到,获得积分10
24秒前
nine2652完成签到 ,获得积分10
25秒前
烂漫的睫毛完成签到 ,获得积分10
27秒前
量子星尘发布了新的文献求助10
27秒前
陈老太完成签到 ,获得积分10
28秒前
宇宇宇c完成签到,获得积分10
29秒前
zxt完成签到,获得积分10
30秒前
大橙子发布了新的文献求助10
33秒前
聪明静柏完成签到 ,获得积分10
35秒前
kimiwanano完成签到,获得积分10
37秒前
lu完成签到,获得积分10
38秒前
Profeto应助齐嫒琳采纳,获得10
39秒前
40秒前
情怀应助科研通管家采纳,获得10
41秒前
从来都不会放弃zr完成签到,获得积分10
45秒前
1459完成签到,获得积分10
47秒前
行者+完成签到,获得积分10
47秒前
GongSyi完成签到 ,获得积分10
48秒前
Boris完成签到 ,获得积分10
50秒前
哭泣笑柳完成签到,获得积分10
50秒前
万能图书馆应助大橙子采纳,获得10
53秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038157
求助须知:如何正确求助?哪些是违规求助? 3575869
关于积分的说明 11373842
捐赠科研通 3305650
什么是DOI,文献DOI怎么找? 1819255
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022