Approaching the High-Risk Patient: Sublobar Resection, Stereotactic Body Radiation Therapy, or Radiofrequency Ablation

医学 烧蚀 射频消融术 放射科 放射外科 放射治疗 切除术 外科 内科学
作者
Hiran C. Fernando,Mathew J. Schuchert,Rodney J. Landreneau,Benedict D.T. Daly
出处
期刊:The Annals of Thoracic Surgery [Elsevier]
卷期号:89 (6): S2123-S2127 被引量:23
标识
DOI:10.1016/j.athoracsur.2010.02.101
摘要

Patients with clinical stage I lung cancer can be considered as arising from three treatment groups: (1) good-risk patients, who are usually treated with lobectomy; (2) high-risk patients, who are usually treated with sublobar (segmental or wedge) resection; and (3) medically inoperable patients, who have traditionally been treated with external beam radiation. Stereotactic body radiation therapy and radiofrequency ablation are two approaches that are gaining increasing popularity for medically inoperable patients. Some have even argued that stereotactic body radiation therapy may be equivalent to lobectomy because of equivalent local control. This assumption is incorrect, because the definitions of local control in the surgical, radiation oncology, and radiology literature are not the same. At best, stereotactic body radiation therapy and radiofrequency ablation can only approximate a wedge resection if it is assumed that 100% tumor destruction has occurred. Lymph node dissection and sampling can also be undertaken at the time of sublobar resection, potentially improving outcomes and allowing identification of unsuspected nodal disease. Despite this, stereotactic body radiation therapy and radiofrequency ablation may be clinically equivalent to sublobar resection for the high-risk patient because of lower procedural morbidity and more rapid return to normal function; however, this has not yet been determined in prospective studies. We review current data on oncologic and secondary outcomes such as morbidity and effect on pulmonary function to help define which therapy is best.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI

祝大家在新的一年里科研腾飞
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
EXCELSIOR发布了新的文献求助10
1秒前
shelemi发布了新的文献求助10
3秒前
shilong.yang发布了新的文献求助10
4秒前
享音发布了新的文献求助10
5秒前
多摩川的烟花少年完成签到,获得积分10
5秒前
阳佟半仙发布了新的文献求助10
7秒前
jjq完成签到,获得积分10
8秒前
12秒前
卓天宇完成签到,获得积分10
13秒前
14秒前
14秒前
16秒前
17秒前
橙鹿鹿的猫完成签到,获得积分10
19秒前
万能图书馆应助享音采纳,获得10
19秒前
19秒前
zlfan2197发布了新的文献求助10
19秒前
19秒前
JUN发布了新的文献求助10
20秒前
20秒前
gc完成签到,获得积分10
20秒前
lonelymusic发布了新的文献求助30
21秒前
lht完成签到 ,获得积分10
22秒前
看看文献吧完成签到,获得积分10
23秒前
周周发布了新的文献求助10
23秒前
23秒前
gc发布了新的文献求助10
24秒前
天真念柏发布了新的文献求助10
25秒前
EXCELSIOR完成签到,获得积分10
25秒前
暴躁的嘉懿完成签到,获得积分10
25秒前
shenzhou9发布了新的文献求助10
26秒前
xiuxiuzhang完成签到 ,获得积分10
27秒前
科研通AI2S应助周周采纳,获得10
28秒前
shdfio应助周周采纳,获得10
28秒前
28秒前
天天快乐应助wangjunhao采纳,获得10
30秒前
30秒前
FireNow完成签到 ,获得积分10
31秒前
思源应助积极雁采纳,获得10
31秒前
32秒前
高分求助中
Востребованный временем 2500
The Three Stars Each: The Astrolabes and Related Texts 1500
Classics in Total Synthesis IV: New Targets, Strategies, Methods 1000
Les Mantodea de Guyane 800
Mantids of the euro-mediterranean area 700
The Oxford Handbook of Educational Psychology 600
有EBL数据库的大佬进 Matrix Mathematics 500
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 内科学 物理 纳米技术 计算机科学 遗传学 化学工程 基因 复合材料 免疫学 物理化学 细胞生物学 催化作用 病理
热门帖子
关注 科研通微信公众号,转发送积分 3414346
求助须知:如何正确求助?哪些是违规求助? 3016425
关于积分的说明 8876599
捐赠科研通 2704273
什么是DOI,文献DOI怎么找? 1482596
科研通“疑难数据库(出版商)”最低求助积分说明 685467
邀请新用户注册赠送积分活动 680251