Synthesis of Fluoroalkyl Cyclopentenes: Highly Diastereoselective Phosphine‐Catalyzed [3+2] Annulation of β‐Fluoroalkylvinyl Arylsulfones with Morita‐Baylis‐Hillman Carbonates

Abstract A phosphine‐catalyzed [3+2] annulation of β‐fluoroalkylvinyl arylsulfones and Morita‐Baylis‐Hillman carbonates was achieved to generate tetrasubstituted cyclopentene carboxylates with a fluoroalkylated stereogenic center at C4. The substrates with various substituents provided the expected [3+2] products in generally excellent yields and diastereoselectivities. This transformation provides a simple and efficient method for the synthesis of fluoroalkyl‐substituted cyclopentene compounds.