眼阻
弱点
医学
肌肉无力
物理医学与康复
眼科
外科
解剖
上睑下垂
作者
Thapat Wannarong,Karra A. Jones,Natalia González
出处
期刊:Neurology
[Lippincott Williams & Wilkins]
日期:2024-08-13
卷期号:103 (3)
标识
DOI:10.1212/wnl.0000000000209708
摘要
The clinical assessment of patients with proximal muscle weakness represents a frequent yet intricate challenge. We present the case of a 60-year-old woman who experienced a progressive, symmetrical weakness in proximal limbs and bulbar muscles over 6 months. Notable clinical findings included bilateral ophthalmoparesis; widespread muscle atrophy; and pronounced weakness in craniobulbar, cervical, and proximal muscles, more severe than in distal ones. We elucidate a methodical diagnostic approach, focusing on constructing a comprehensive differential diagnosis and identifying potential causes of proximal muscle weakness. Special emphasis is placed on exploring the etiologies in cases presenting with both progressive muscle weakness and ophthalmoparesis. We further describe the role of muscle biopsy results and their integration with genetic testing outcomes.
科研通智能强力驱动
Strongly Powered by AbleSci AI