Wire and arc additive manufacturing (WAAM) technique has introduced a novel approach for producing complex Ti–6Al–4V parts with metric dimensions. However, the produced part leads to the development of a strong texture and anisotropic mechanical properties due to the formation of large columnar β grains. To resolve this issue, the plastic deformation of each deposited track through hammer peening was developed as a means to refine these large β grains. In this study, we have investigated an innovative approach to further enhance the efficiency of β grain refinement by minimizing the arc heat input associated with previous deposited layer, which is achieved by employing a C-type filler wire. Our findings reveal a notable enhancement in grain refinement efficiency through the utilization of a C-type filler wire with peening process, as compared to available conventional commercial round shape filler wire. Specifically, the employment of the C-type filler wire results in a reduced melt pool penetration depth of WAAM Ti–6Al–4V (3.3 mm), compared to the commercially available round shape (R-Type) filler wire (4.48 mm). Within the plastically deformed region by peening, fine and randomly oriented β grains are observed, extending to a depth of deformation reaching 844 ± 32.65 μm. Peening WAAM Ti–6Al–4V with the C-type filler wire leads to the development of isotropic mechanical properties in both horizontal and vertical directions, offering high strength due to the presence of small equiaxed β grains and thin α laths (0.56 ± 0.18 μm), in contrast to the use of conventional commercial round shape filler wire.