医学
秋水仙碱
造血
突变体
癌症研究
突变
细胞生物学
免疫学
遗传学
内科学
干细胞
基因
生物
作者
María A. Zuriaga,Zhi Yu,Nuria Matesanz,Buu Truong,Beatriz López Ramos-Neble,M. Lopez,Md Mesbah Uddin,Tetsushi Nakao,Abhishek Niroula,Virginia Zorita,Marta Amorós-Pérez,Rosa Moro,Benjamin L. Ebert,Michael C. Honigberg,Domingo A. Pascual‐Figal,Pradeep Natarajan,José J. Fuster
标识
DOI:10.1093/eurheartj/ehae546
摘要
These results highlight the potential value of colchicine to mitigate the higher cardiovascular risk of carriers of somatic TET2 mutations in blood cells. These observations set the basis for the development of clinical trials that evaluate the efficacy of precision medicine approaches tailored to the effects of specific mutations linked to CH.
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