Six pairs of α-pyrone meroterpenoid dimers from Hypericum monogynum with anti-neuroinflammatory activity

Hypericumonates A–C, the first α-pyrone meroterpenoid dimers with two motifs (a 6/6/4-6/6 ring system) connected via C-8–C-9, were isolated from Hypericum monogynum . (+)-1 exhibited good anti-neuroinflammatory activity.