Intratumoral and peritumoral radiomics based on ultrasound for the differentiation of follicular thyroid neoplasm

Although ultrasound (US) has been widely adopted as the preferred imaging modality for thyroid nodule evaluation, its reliability in distinguishing follicular adenomas from adenocarcinomas based on US features has been a subject of debate. The primary objective of our study was to comprehensively evaluate the efficacy of US-derived intratumoral and peritumoral radiomics in preoperatively differentiating follicular thyroid adenomas from adenocarcinomas, thereby contributing to the ongoing discussion regarding this challenging distinction.