清脆的
电流(流体)
生物
计算生物学
计算机科学
基因
风险分析(工程)
数据科学
遗传学
业务
工程类
电气工程
作者
Elizabeth H. Kellogg,Jonathan S. Gootenberg,Omar O. Abudayyeh,Alan S.L. Wong,James E. Dahlman,Audrone Lapinaite,Cameron Myhrvold,Chang C. Liu,Patrick Hsu,Prashant Mali,Lei Qi
出处
期刊:Cell systems
[Elsevier]
日期:2022-08-01
卷期号:13 (8): 589-593
标识
DOI:10.1016/j.cels.2022.07.004
摘要
I think of CRISPR as being a subset of “adaptive” bacterial systems that promote host survival. These adaptive systems are macromolecular systems that enhance host survival in a myriad of ways: by destroying foreign DNA, by mediating horizontal gene transfer, or even by altering host metabolism, among many other diverse functions. In this sense, CRISPR represents just the tip of the iceberg; there are likely many unexplored and uncharacterized adaptive systems that would be practically useful for genomic manipulation.
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