亲爱的研友该休息了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!身体可是革命的本钱,早点休息,好梦!

Role of Additional MRI‐Based Morphologic Measurements on the Performance of VI‐RADS for Muscle‐Invasive Bladder Cancer

医学 膀胱癌 接收机工作特性 置信区间 优势比 磁共振成像 核医学 逻辑回归 癌症 曲线下面积 泌尿科 放射科 内科学
作者
Yu Gong,Yi Cheng,Jing Zhang,Meiling Bao,Feipeng Zhu,Xueying Sun,Yu‐Dong Zhang
出处
期刊:Journal of Magnetic Resonance Imaging [Wiley]
卷期号:60 (3): 1113-1123 被引量:1
标识
DOI:10.1002/jmri.29184
摘要

Background Vesical Imaging‐Reporting and Data System (VI‐RADS) is a pathway for the standardized imaging and reporting of bladder cancer staging using multiparametric (mp) MRI. Purpose To investigate additional role of morphological (MOR) measurements to VI‐RADS for the detection of muscle‐invasive bladder cancer (MIBC) with mpMRI. Study Type Retrospective. Population A total of 198 patients (72 MIBC and 126 NMIBC) underwent bladder mpMRI was included. Field Strength/Sequence 3.0 T/T2‐weighted imaging with fast‐spin‐echo sequence, spin‐echo‐planar diffusion‐weighted imaging and dynamic contrast‐enhanced imaging with fast 3D gradient‐echo sequence. Assessment VI‐RADS score and MOR measurement including tumor location, number, stalk, cauliflower‐like surface, type of tumor growth, tumor‐muscle contact margin (TCM), tumor‐longitudinal length (TLL), and tumor cellularity index (TCI) were analyzed by three uroradiologists (3‐year, 8‐year, and 15‐year experience of bladder MRI, respectively) who were blinded to histopathology. Statistical Tests Significant MOR measurements associated with MIBC were tested by univariable and multivariable logistic regression (LR) analysis with odds ratio (OR). Area under receiver operating characteristic curve (AUC) with DeLong's test and decision curve analysis (DCA) were used to compared the performance of unadjusted vs. adjusted VI‐RADS. A P ‐value <0.05 was considered statistically significant. Results TCM (OR 9.98; 95% confidence interval [CI] 4.77–20.8), TCI (OR 5.72; 95% CI 2.37–13.8), and TLL (OR 3.35; 95% CI 1.40–8.03) were independently associated with MIBC at multivariable LR analysis. VI‐RADS adjusted by three MORs achieved significantly higher AUC (reader 1 0.908 vs. 0.798; reader 2 0.906 vs. 0.855; reader 3 0.907 vs. 0.831) and better clinical benefits than unadjusted VI‐RADS at DCA. Specially in VI‐RADS‐defined equivocal lesions, MOR‐based adjustment resulted in 55.5% (25/45), 70.4% (38/54), and 46.4% (26/56) improvement in accuracy for discriminating MIBC in three readers, respectively. Data Conclusion MOR measurements improved the performance of VI‐RADS in detecting MIBC with mpMRI, especially for equivocal lesions. Level of Evidence 3 Technical Efficacy Stage 2
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
9秒前
祖之微笑发布了新的文献求助10
14秒前
量子星尘发布了新的文献求助10
19秒前
25秒前
48秒前
54秒前
1分钟前
1分钟前
33应助可靠的寒风采纳,获得20
1分钟前
量子星尘发布了新的文献求助10
1分钟前
1分钟前
JamesPei应助背后梦安采纳,获得10
1分钟前
2分钟前
祖之微笑发布了新的文献求助10
2分钟前
祖之微笑完成签到,获得积分10
2分钟前
2分钟前
Magali发布了新的文献求助10
2分钟前
2分钟前
3分钟前
3分钟前
shinian完成签到,获得积分10
3分钟前
shinian发布了新的文献求助10
3分钟前
3分钟前
3分钟前
哈尔滨发布了新的文献求助10
3分钟前
背后梦安发布了新的文献求助10
3分钟前
量子星尘发布了新的文献求助10
3分钟前
3分钟前
zhen完成签到,获得积分10
4分钟前
哈尔滨完成签到,获得积分20
4分钟前
4分钟前
米奇妙妙屋完成签到,获得积分10
4分钟前
tylscxf完成签到,获得积分10
4分钟前
YifanWang完成签到,获得积分0
4分钟前
量子星尘发布了新的文献求助30
5分钟前
5分钟前
启震发布了新的文献求助10
5分钟前
5分钟前
5分钟前
5分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976649
求助须知:如何正确求助?哪些是违规求助? 3520756
关于积分的说明 11204743
捐赠科研通 3257502
什么是DOI,文献DOI怎么找? 1798733
邀请新用户注册赠送积分活动 877897
科研通“疑难数据库(出版商)”最低求助积分说明 806629