Reply to: Minocycline versus tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori rescue treatment: a multicentre, randomized controlled trial

3-5], accounting for the high incidence of adverse events in our study as well.Certainly, a good regimen for H. pylori eradication should accomplish satisfactory outcomes with low side effects.Therefore, we also conducted another study to explore the efficacy and tolerability of the lower dosage of minocycline and metronidazole in bismuth-containing quadruple therapy for H. pylori eradication and relevant data are being collected for further analysis.