A rapid and greener MOF-2 catalyzed Knoevenagel reaction at room temperature

An efficient MOF-2 [Zn2(BDC)2] catalyzed process of Knoevenagel reaction has developed at room temperature using an eco-friendly reaction medium. The different substituted aldehydes studied with malononitrile as substrates and the derivatives were obtained in excellent yields with good tolerance of functional groups in the established Knoevenagel condensation approach.