Quorum Sensing and Quorum Quenching: Two sides of the same coin

Quorum Sensing (QS) is a type of cell-to-cell microbial communication system induced by certain molecules known as auto-inducers which are required for important regulatory functions like the production of virulence factors, sporulation, conjugation, infections and invasions, colonization, biofilm formation, and antibiotic resistance within bacterial populations. On the other hand, Quorum Quenching (QQ) is a process that causes the alleviation of virulence factors and inhibition of quorum-sensing molecules. The survival of plant growth-promoting rhizobacteria in presence of continuously invading pathogens creates a need for strategies that could help them activate their defense mechanisms and be at par with the pathogens. The modulation of quorum quenching enzymes and quorum sensing molecules can thus be useful in determining the Biocontrol potential of Plant growth promoting rhizobacteria (PGPR) strain and these processes could further be used as sustainable agronomic approaches to damper the disease-causing agents and promote crop recovery.