医学
内科学
急性冠脉综合征
甘油三酯
再狭窄
胰岛素抵抗
胃肠病学
单变量分析
心脏病学
冠状动脉支架
多元分析
支架
胰岛素
胆固醇
心肌梗塞
作者
Yingle Wu,Laijing Du,Mengnan Fan,Chen Xinzhao,Yanyan Tang,Yanyu Wang,Ke Wang,Shaoxin Wang,Guangping Li
出处
期刊:Oral Diseases
[Wiley]
日期:2022-11-16
卷期号:29 (8): 3698-3706
被引量:5
摘要
To investigate oral infections in patients suffering in-stent restenosis (ISR) and non-ISR and analyze the possible correlation between the oral infection and triglyceride-glucose (TyG) index, a clinical surrogate indicator of insulin resistance (IR).A cross-sectional design was used, in which 586 patients with acute coronary syndrome who underwent coronary angiography 6-24 months after coronary stent implantation were recruited. The modified total dental index (TDI) was used to evaluate the status of oral inflammation.In both univariate analyses, TDI scores [3 (1.5, 4.5) vs. 2.5 (1.5, 4.0), p < 0.01] and a multivariate regression model (OR = 1.202, 95% CI = 1.085-1.333, p < 0.01), the TDI significantly correlated with ISR. The TyG index was positively associated with ISR (OR = 1.766, 95% CI = 1.055-2.957, p < 0.05). Correlation analysis showed that TDI was positively correlated with TyG index (r = 0.190, p < 0.01). Using linear regression analysis, higher TDI scores were significantly associated with IR (95% CI = 0.029-0.063, p < 0.01).Oral infections and TyG index were independently and positively correlated with ISR in patients with acute coronary syndrome. Oral inflammatory burden assessed by TDI score was associated with IR.
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