To assess the postoperative quality of life and prognosis of patients with intracranial aneurysm (IA) after nursing based on a time-based concept.Data of 84 patients with IA who underwent treatment at the Shengjing Hospital Affiliated to China Medical University from February 2019 to February 2021 were analyzed retrospectively. Among them, the control group (n=41) received conventional nursing. On this basis, the observation group (n=43) received nursing based on the concept of time. Patients' limb motor function and quality of life before and after treatment, postoperative complications and prognosis, and nursing satisfaction were evaluated. Also, risk factors for poor prognosis were analyzed through multifactorial analysis.One month after surgery, the scores of Fugl-Meyer Assessment (FMA) and Quality-of-Life Questionnaire Core in both groups were higher than those before nursing, and both scores were dramatically higher in the observation group than in the control group (P<0.05). The overall postoperative complication rate was markedly higher in the control group than in the observation group (P<0.05). Patients in the observation group were more satisfied with the nursing than those in the control group (P<0.05). The postoperative prognosis in the observation group was dramatically better than that in the control group (P<0.05). There were statistical differences in age, timing of intervention, hypertension, aneurysm diameter, Hunt-Hess classification, Fisher grade, FMA score and nursing regimen at one month postoperatively between the good prognosis group and the poor prognosis group (P<0.05). Older age, delayed timing of intervention, aneurysm ≥15 mm and Fisher grade ≥3 were independent risk factors for poor prognosis.In summary, a nursing model based on the concept of time can effectively improve the rehabilitation outcome, improve the prognosis, and enhance the quality of life in IA patients.