An enzyme-free glucose sensing device based on TiO2 nanorod array photoelectric catalysis

A simple one-step hydrothermal method is used to prepare an enzyme-free photoelectric combined glucose sensor based on TiO2NRs/FTO with low cost, sample two-electrode, and excellent detection. Under 380 nm light (0.5 mW cm−2) irradiation and a positive voltage, holes are accumulated on TiO2NRs surface, catalyzing glucose and forming a photocurrent without the need for an enzyme, such as Glucose oxidase (GOx). The designed sensor exhibits high sensitivity (about 0.96 μA mM−1 cm−2, without GOx) and excellent linear relationship in the glucose concentration range of 5–15 mML−1. The prepared glucose sensor performs better with a sensitivity of 1.48 μA mM−1 cm−2 when a certain amount of GOx is mixed in the detected solution. In addition, the sensor has excellent anti-interference resistance to non-reducing chitosan and reducing ascorbic acid with short response time (less than 5 s); thus, it can be used in quick detection with a double electrode system. This sensing device has the advantages of simple fabrication, easy storage, and reusability; therefore, it can be very promising in the portable and rapid monitoring of human blood glucose levels.