生物相容性
材料科学
聚乙烯醇
纳米技术
抗菌活性
生物电子学
自愈水凝胶
银纳米粒子
纳米颗粒
复合材料
生物传感器
细菌
高分子化学
生物
冶金
遗传学
作者
Hsin Cheng,Ramadhass Keerthika Devi,Kuan‐Yeh Huang,Muthusankar Ganesan,Sai Kishore Ravi,Chun Che Lin
出处
期刊:Small
[Wiley]
日期:2024-06-07
被引量:1
标识
DOI:10.1002/smll.202401201
摘要
Abstract Flexible electronics, like electronic skin (e‐skin), rely on stretchable conductive materials that integrate diverse components to enhance mechanical, electrical, and interfacial properties. However, poor biocompatibility, bacterial infections, and limited compatibility of functional additives within polymer matrices hinder healthcare sensors' performance. This study addresses these challenges by developing an antibacterial hydrogel using polyvinyl alcohol (PVA), konjac glucomannan (KGM), borax (B), and flower‐shaped silver nanoparticles (F‐AgNPs), referred as PKB/F‐AgNPs hydrogel. The developed hydrogel forms a hierarchical network structure, with a tensile strength of 96 kPa, 83% self‐healing efficiency within 60 minutes, and 128% cell viability in Cell Counting Kit‐8 (CCK‐8) assays, indicating excellent biocompatibility. It also shows strong antibacterial efficacy against Gram‐negative Escherichia coli ( E. coli ) and Gram‐positive Staphylococcus aureus ( S. aureus ). Blue light irradiation enhances its antibacterial activity by 1.3‐fold for E. coli and 2.2‐fold for S. aureus . The hydrogel's antibacterial effectiveness is assessed by monitoring changes in electrical conductivity, providing a cost‐effective alternative to traditional microbial culture assays. The PKB/F‐AgNPs hydrogel's flexibility and electrical conductivity enable it to function as strain sensors for detecting body movements and facial expressions. This antibacterial hydrogel underscores its potential for future human‐machine interfaces and wearable electronics.
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