Remimazolam versus propofol for sedation in gastrointestinal endoscopic procedures: a systematic review and meta-analysis. Comment on Br J Anaesth 2024; 132: 1219–29

Editor—We read with interest the study by Barbosa and colleagues. 1 Barbosa E.C. Espírito Santo P.A. Baraldo S. Meine G.C. Remimazolam versus propofol for sedation in gastrointestinal endoscopic procedures: a systematic review and meta-analysis. Br J Anaesth. 2024; 132: 1219-1229 Google Scholar This study pooled information on efficacy, safety, and satisfaction outcomes between remimazolam, a novel sedative, and propofol in sedation for gastrointestinal endoscopy. Remimazolam was found to have a superior safety profile compared with propofol for sedating adults undergoing gastrointestinal endoscopy. This was observed in both younger and older populations. Remimazolam versus propofol for sedation in gastrointestinal endoscopic procedures: a systematic review and meta-analysisBritish Journal of AnaesthesiaVol. 132Issue 6PreviewPropofol has a favourable efficacy profile in gastrointestinal endoscopic procedures, however adverse events remain frequent. Emerging evidence supports remimazolam use in gastrointestinal endoscopy. This systematic review and meta-analysis compares remimazolam and propofol, both combined with a short-acting opioid, for sedation of adults in gastrointestinal endoscopy. Full-Text PDF