The single-probe mass spectrometry for single cell analysis and biological tissue imaging

Mass spectrometry (MS) is commonly used to analyze the molecular composition of prepared gas-phase or solution samples. With the recent development, MS has been used to obtain the cellular composition of single cell (i.e. single cell MS) and map the spatial distribution of species on biological tissues (i.e. MS imaging). We have developed a multifunctional device, named as the Single-probe. This device can be coupled with MS for multiple applications, including single cell MS and MS imaging.