China's present situation and developing trend of biological pharmaceutical industry research

制药工业 中国 业务 药学 计算机科学 药理学 政治学 医学 法学
作者
Wei Long,Jiping Wei,Haisong Yin,Zhiheng Pan
标识
DOI:10.2991/icemct-17.2017.158
摘要

the biological pharmaceutical industry is a sun-rising industry, broad prospects for many countries are planning as its key domestic development, biological pharmaceutical industry will become the future of world science and technology and economic competition strategic high ground.This article more comprehensively introduces the research progress of biological pharmaceutical industry in China, discussed the existing problems in biomedical research in China, a certain amount of settlement, and proposed. The Progressing Research In Biological Pharmaceutical In Our CountryBiochemical drugs refers to the biological chemistry, on the basis of research results, using organisms play an important role in all kinds of basic material, through some means such as extraction, separation and purification of developed bioactive substances, such as amino acids, peptides, proteins, enzymes, coenzyme, grease, polysaccharide, nucleotides and biogenic amine, etc., and their derived structure[3], at present our country has been on the study of biochemical drugs have a certain progress: in inhibiting tumor growth, resisting thrombosis, cerebral hemorrhage clinical application, resist fatigue, in the treatment of osteoarthritis, etc have gained some research success [4,5].Dong He etc.[6] sitosterol from hawthorn extract and appraisal, and to three kinds of tumor cells in logarithmic phase (Heps, S180 and EAC) and one kind of human normal liver cells (L02) the MIT proliferation and DNA gel electrophoresis experiments, the role of research sitosterol in these four cells.Gel electrophoresis results: no DNA ladder with blank control group, the other three groups are different levels of DNA ladder belt, showed the characteristics of cell apoptosis.The experiment results show that: a certain concentration of sitosterol in vitro culture of Heps, S180 and EAC cells have the effect of the inhibition, no obvious inhibitory effect to the body's cells.Thus draw the conclusion: sitosterol is probably by promoting tumor cell apoptosis to curb its breeding, further verify the function of plant sitosterol has antitumor [7].Genetic engineering drugs production is generally determined by the first of a disease prevention and treatment effect of protein, then using restriction enzymes and exogenous gene from the control of the process of protein synthesis genes, again through DNA ligase and gene carrier (plasmid, bacteriophages, viruses) DNA, connection, and then turn to microorganisms or cells for cloning, and makes the purpose gene eventually successful expression within the host cell, achieve the desired protein [8].The first generation of genetic engineering drugs mainly for lack of natural endogenous protein caused by disease, application of genetic engineering technology to expand the production of this kind of polypeptide protein to replace or supplement the body's need for this type of active polypeptide protein.Is the second type of genetic engineering drugs according to the physiological
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