中肠
神经内分泌肿瘤
医学
生长抑素受体
生长抑素
放射性核素治疗
内科学
生长抑素受体2
镥
癌症研究
肿瘤科
病理
内分泌学
生物
幼虫
有机化学
化学
钇
氧化物
植物
作者
Jonathan Strosberg,Ghassan El‐Haddad,Edward M. Wolin,Andrew Hendifar,James C. Yao,Beth Chasen,Erik Mittra,Pamela L. Kunz,Matthew H. Kulke,Heather A. Jacene,David Bushnell,Thomas M. O’Dorisio,Richard P. Baum,Harshad Kulkarni,Martyn Caplin,Rachida Lebtahi,Timothy J. Hobday,Ebrahim S. Delpassand,Eric Van Cutsem,Al B. Benson
标识
DOI：10.1056/nejmoa1607427
摘要
Patients with advanced midgut neuroendocrine tumors who have had disease progression during first-line somatostatin analogue therapy have limited therapeutic options. This randomized, controlled trial evaluated the efficacy and safety of lutetium-177 (177Lu)–Dotatate in patients with advanced, progressive, somatostatin-receptor–positive midgut neuroendocrine tumors.
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