细胞凋亡
程序性细胞死亡
癌症
癌细胞
索拉非尼
细胞
PI3K/AKT/mTOR通路
肾透明细胞癌
ATG5型
生物
标识
DOI:10.3389/fphar.2020.518225
摘要
Autophagy is a process that degrades and recycles superfluous organelles or damaged cellular contents. It has been found to have dual functions in renal cell carcinoma (RCC). Many autophagy-related proteins are regarded as prognostic markers of RCC. Researchers have attempted to explore synthetic and phytochemical drugs for RCC therapy that target autophagy. In this review, we highlight the importance of autophagy in RCC and potential treatments related to autophagy.
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