Research advence of biofilms of Aspergillus

The mortality causing by fungal biofilms has already made doctors pay attention to Candida albicans is the most famous one of all fungal biofilm formers. However, non-Candida species,yeasts such as Cryptococcus neoformans, and filamentous moulds such as Aspergillus fumigatus, have been shown to be implicated in biofilm-associated infections. Fungal biofilms have distinct developmental phases, including adhesion, colonisation, maturation and dispersal, which are governed by complex molecular events. Recalcitrance to antifungal therapy remains the greatest threat to patients with fungal biofilms. Key words: Fungal; Biofilm; Antifungal