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Editorials1 November 1995Stalking SarcopeniaIrwin H. Rosenberg, MD and Ronenn Roubenoff, MD, MHSIrwin H. Rosenberg, MDTufts University Boston, MA 02111 and Ronenn Roubenoff, MD, MHSTufts University Boston, MA 02111Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-123-9-199511010-00014 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Among the most dramatic biological markers of increasing age are changes in body composition. Although weight may remain stable or increase somewhat throughout adulthood, fat-free mass steadily decreases and fat mass as a percentage of body weight therefore increases [1]. This age-related change is even more impressive if the decrease in muscle mass is measured rather than the decrease in lean body mass or fat-free mass, which includes viscera and bone. The rate of decline by decade is particularly great after age 70 years; this can be confirmed by direct regional assessments of the cross-sectional area of skeletal muscle in ...References1. Heymsfield SB, Cohn SH. Changes in body composition with age. In: Watkins JC, Roubenoff R, Rosenberg IH, eds. Body Composition: The Measure and Meaning of Changes with Aging. Boston: Foundation for Nutritional Advancement; 1992:1-11. Google Scholar2. Poehlman ET, Toth MJ, Gardner AW. Changes in energy balance and body composition at menopause: a controlled longitudinal study. Ann Intern Med. 1995; 123:673-5. Google Scholar3. Aloia JF, McGowan DM, Vaswani AN, Ross P, Cohn SH. Relationship of menopause to skeletal and muscle mass. Am J Clin Nutr. 1991; 53:1378-83. Google Scholar4. Rosenberg IH. Summary comments: epidemiological and methodological problems in determining nutritional status of older persons. Am J Clin Nutr. 1989; 50:1231-3. Google Scholar5. Frantz AG, Rabkin MT. 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Roberts SH, Fuss P, Heyman MB, Evans WJ, Tsay R, Rasmussen H, et al. Control of food intake in older men. JAMA. 1994; 272:1601-6. Google Scholar11. Fiatarone MA, Marks EC, Ryan ND, Meredith CN, Lipsitz LA, Evans WJ. High-intensity strength training in nonagenarians. Effects on skeletal muscle. JAMA. 1990; 263:3029-34. Google Scholar12. Fiatarone MA, Evans WJ, Neill E, Lipsitz L, Roberts SB. The Boston FICSIT Study: the effects of resistance training and nutritional supplementation on physical frailty in the oldest old. J Am Geriatr Soc. 1993; 333. Google Scholar Author, Article, and Disclosure InformationAuthors: Irwin H. Rosenberg, MD; Ronenn Roubenoff, MD, MHSAffiliations: Tufts University Boston, MA 02111Current Author Addresses: Drs. Rosenberg and Roubenoff: Jean Mayer U.S. Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, 711 Washington Street, Boston, MA 02111. 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