表型筛选
药物发现
鉴定(生物学)
数据科学
计算生物学
表型
生物
计算机科学
生物信息学
遗传学
基因
植物
出处
期刊:The Royal Society of Chemistry eBooks
[The Royal Society of Chemistry]
日期:2020-12-09
被引量:7
标识
DOI:10.1039/9781839160721
摘要
Phenotypic drug discovery has been highlighted in the past decade as an important strategy in the discovery of new medical entities. How many marketed drugs are derived from phenotypic screens? From the most recent examples, what were the factors enabling target identification and validation? This book answers these questions by elaborating on fundamental capabilities required for phenotypic drug discovery and using case studies to illustrate approaches and key success factors. Written and edited by experienced practitioners from both industry and academia, this publication will equip researchers with a thought-provoking guide to the application and future development of contemporary phenotypic drug discovery for clinical success.
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